Pulmonary function testing has been a well-known and relatively accessible test for all specialists in respirology for more than half a century. Since the beginning of the 21st century, recent breakthroughs in molecular biology and high throughput gene analysis technologies have progressively led us to a new and exciting era of modern personalized medicine. Yet, lung function testing still keeps its value as a practical, easily performed and most valuable tool helping respiratory physicians to better characterize patients’ phenotypes based on individual respiratory function, that now includes quantitative and qualitative assessment of breath. In this short review, we will attempt to briefly summarize the most recent developments in this field.

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